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The effect of vaccination of lambs with live parainfluenza virus type 3 on pneumonia produced by parainfluenza virus type 3 and Pasteurella haemolytica

The effect of vaccination of lambs with live parainfluenza virus type 3 on pneumonia produced by parainfluenza virus type 3 and Pasteurella haemolytica
Peer reviewed
Davies DH, McCarthy AR, Penwarden RA
New Zealand Veterinary Journal, Volume 28, Issue 10, pp 201-202, Oct 1980

Article class: Scientific Article

Subject Terms: Animal remedies/veterinary medicines, Bacterial, Disease/defect, Immune system/immunology, Infectious disease, Notifiable organisms/exotic disease, Pneumonia/pleurisy, Research/development, Respiratory system, Vaccination, Viral

Animal Type: Livestock, Production animal, Ruminant, Sheep

Publisher: Taylor and Francis

Abstract

Groups of 20 lambs were vaccinated with parainfluenza virus type 3 (PI3) by the intranasal (I.N.) or intramuscular route (I.M.). Approximately 6 weeks later, vaccinated and nonvaccinated lambs were challenged sequentially with PI3 and Pasteurella haemolytica. At slaughter, 10 to 12 days after challenge, 65% of non-vaccinates and 45% of I.M. vaccinates had pneumonic lesions whereas lesions were not observed in any of the I.N. vaccinates.

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