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Lafora's disease in an epileptic Basset hound

Lafora's disease in an epileptic Basset hound
Peer reviewed
Jian Z, Alley MR, Cayzer J, Swinney GR
New Zealand Veterinary Journal, Volume 38, Issue 2, pp 75-79, Jun 1990

Article class: Clinical Communication

Animal Type: Companion animal, Dog

Subject Terms: Disease/defect, Locomotor, Nervous system/neurology, Pathology

Publisher: Taylor and Francis

Abstract

A 6-year-old Basset hound developed a progressive central nervous system disease culminating in epileptic seizures. Histologically, Lafora bodies were found in neurones of the middle and deeper cerebral cortex and midbrain, in Purkinje cells and their processes, and in glial cells of the molecular layer of the cerebellum. Many were also observed free in the neuropil. The ultrastructural and histochemical characteristics of the bodies were similar to those described in previous human and canine cases of Lafora`s disease.

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