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Field studies investigating anthelmintic resistance in young cattle on five farms in New Zealand
Mason PC, McKay CH
New Zealand Veterinary Journal, Volume 54, Issue 6, pp 318-322, Dec 2006
New Zealand Veterinary Journal, Volume 54, Issue 6, pp 318-322, Dec 2006
Article class: Scientific Article
Subject Terms: Alimentary system/gastroenterology, Animal remedies/veterinary medicines, Anthelmintics, Biosecurity, Diagnostic procedures, Disease surveillance, Farm/farm management, Nematode, Parasite control, Parasites - internal, Survey, Treatment/therapy
Animal Type: Livestock, Production animal, Ruminant, Sheep
Publisher: Taylor and FrancisAbstract
AIM: To investigate the efficacy of pour-on anthelmintics against field strains of parasitic nematodes in young cattle on five farms in New Zealand.METHODS: Faecal nematode egg count (FEC) reduction (FECR) tests were carried out on five calf-rearing farms using pour-on formulations of levamisole, ivermectin, eprinomectin, and the simultaneous administration of levamisole and ivermectin. Faecal samples were collected per rectum before treatment and about 7, 14, 21 and 28 days after treatment, for FEC and faecal nematode larval culture.
RESULTS: Resistance (i.e. <95% reduction in FEC) of Cooperia oncophora to ivermectin and eprinomectin was identified on all five farms. There was limited evidence of possible emerging resistance in Ostertagia spp to ivermectin but not eprinomectin, in short-tailed larvae of Cooperia spp to ivermectin and eprinomectin, and in Trichostrongylus spp to ivermectin, eprinomectin and levamisole used separately. Levamisole was effective against C. oncophora, but had variable efficacy against Ostertagia spp in the calves in this study. Simultaneous treatment with levamisole and ivermectin pour-on formulations were effective against all genera on all farms.
CONCLUSIONS: To effectively manage roundworm parasites in their calves farmers need to be aware of the resistance status of the parasites on their farms. Levamisole is likely to be an effective anthelmintic on most farms at times of the year when the impact of Ostertagia spp is not high. Simultaneous administration of levamisole and ivermectin pour-on anthelmintics to cattle is likely to control both ML-resistant C. oncophora and stages of Ostertagia spp that are not controlled by levamisole alone.
KEY WORDS: Anthelmintic resistance, cattle, nematode, Cooperia, Ostertagia, Trichostrongylus, levamisole, ivermectin, eprinomectin, macrocyclic lactone, faecal egg count reduction test, faecal larval culture
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