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Combined xeno/auto-grafting of a benign osteolytic lesion in a dog, using a novel bovine cancellous bone biomaterial
Worth AJ, Thompson KG, Owen MC, Mucalo MR, Firth EC
New Zealand Veterinary Journal, Volume 55, Issue 3, pp 143-148, Jun 2007
New Zealand Veterinary Journal, Volume 55, Issue 3, pp 143-148, Jun 2007
Article class: Clinical Communication
Subject Terms: Animal remedies/veterinary medicines, Diagnostic procedures, Imaging, Legal/regulation, Skeletal/bone/cartilage, Surgery
Animal Type: Companion animal, Dog
Publisher: Taylor and FrancisAbstract
CASE HISTORY: A 4-year-old female Labrador Retriever was diagnosed with an osteolytic lesion of the right distal radius.CLINICAL FINDINGS: Radiographs indicated a well-circumscribed radiolucent area 18 x 15 x 8 mm, centred on the distal radial physeal scar.
DIAGNOSIS: Histopathology, performed via Jamshidi needle biopsy and following surgical curettage, was inconclusive but suggested either an aneurysmal bone cyst or fibrous dysplasia.
CLINICAL RELEVANCE: A novel processed cancellous bovine bone xenograft was used in conjunction with autogenous cancellous bone (at a ratio of approximately 4:1) to fill the curetted defect. There were no observed complications associated with the use of this new biomaterial. Osteointegration of the bone graft was followed using conventional radiographs and peripheral quantitative computed tomography (pQCT) for 10 months post-operatively. Radiographically, the osteolytic lesion modelled to resemble metaphyseal trabeculation. The cross-sectional area and the average bone density of the grafted lesion determined using pQCT data increased over time, suggesting healthy osteoconduction and native bone production.
KEY WORDS: Bovine cancellous bone, xenograft
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