Teratogenicity of drugs

Authors: McQueen EG
Publication: New Zealand Veterinary Journal, Volume 20, Issue 9, pp 156-159, Sep 1972
Publisher: Taylor and Francis

Animal type: Livestock
Subject Terms: Animal remedies/veterinary medicines, Congenital disease, Treatment/therapy, Pharmacology
Article class: Review Article

---

Abstract: The thalidomide disaster shook the pharmaceutical world to its foundations. It clearly required that action be taken to prevent by all means possible a recurrence of any similar catastrophe. At the same time, attention was drawn to the occurrence of adverse reactions to drugs of other kinds which had already been the subject of restricted and somewhat sporadic scrutiny, particularly in the United States. There the haematologist, Maxwell Wintrope, had initiated a scheme for collecting reports of haematological reactions to drugs, the importance of which had been brought to the attention of the profession through the cases of aplastic anaemia resulting from the antibiotic chloramphenicol. In Britain, the Committee on Safety of Drugs was formed, of which Sir Derrick Dunlop was the first Chairman, and a subcommittee was set up to deal with the collection of adverse drug reactions…

---