Treatment of acute pancreatitis in the dog: fact or fiction?

Authors: Mansfield C
Publication: Proceedings of the Australian Veterinary Association (AVA) Annual Conferences, Volume 2014 AVA Annual Conference, Perth, Issue Small animal, May 2014
Publisher: Australian Veterinary Association

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Abstract: Pancreatitis develops when there is excessive activation of trypsin and other pancreatic proteases within the pancreas, which then overwhelms local safeguards within the acinar cell. Systemic signs develop due to the activation of multiple inflammatory pathways; and local inflammation ensues due to the influx of neutrophils and the subsequent tissue damage. Clinical signs of pancreatitis are dependent both on the degree of local pancreatic inflammation (pain, vomiting, subsequent dehydration), and the degree of systemic complications (such as cardiac arrhythmias, disseminated intravascular coagulation or acute lung injury)...

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