Coronary heart disease and tocopherol: a viewpoint

Authors: Money DFL, Rammell CG
Publication: New Zealand Veterinary Journal, Volume 24, Issue 6, pp 97-107, Jun 1976
Publisher: Taylor and Francis

Animal type: General
Subject Terms: Circulatory system/haematology, Mortality/morbidity, Vitamins
Article class: Scientific Article

---

Abstract: Coronary heart disease is classically considered to be a consequence of altered blood supply to the myocardium because of atherosclerosis. The WHO (1958) definition of atherosclerosis is “a variable combination of changes in the intima of arteries consisting of the focal accumulation of lipids, complex carbohydrates, blood and blood products, fibrous tissue and calcium deposits, and associated with medial changes”. Furman (1969) has stated that “atherogenesis is one problem, thrombogenesis a second, fatal arrhythmia perhaps a third, and that they may or may not be related. In the final analysis the conclusion seems inescapable that if atherogenesis could be prevented, thrombus formation would be of little or no significance in coronary artery disease, and myocardial infarction would virtually disappear”. Several published observations indicate that atherosclerosis begins very early in life…

---