Mannosidosis - a cause of neonatal mortality in Angus calves

Authors: Jolly RD, Thompson KG
Publication: New Zealand Veterinary Journal, Volume 24, Issue 8, pp 184-185, Aug 1976
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Genetics, Inherited disease/conditions, Nervous system/neurology, Neonatal, Disease/defect
Article class: Clinical Communication

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Abstract: Mannosidosis, a lethal inherited neurological disease associated with a deficiency of the lysosomal enzyme α-mannosidase (Hocking et al 1972) has been described clinically as affecting Angus calves usually in their first year of life (Whittem and Walker, 1957; Jolly, 1970, 1975). Although it has been suspected as a significant cause of neonatal mortality in herds at risk, figures and diagnosis supporting such an hypothesis have not been available.

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