Adaptation of a complement fixation test for large scale serological diagnosis of bovine leptospirosis

Authors: Hodges RT, Weddell W
Publication: New Zealand Veterinary Journal, Volume 25, Issue 10, pp 261-262, Oct 1977
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Bacterial, Clinical pathology, Diagnostic procedures, Immune system/immunology, Zoonosis, Disease/defect, Infectious disease, Public health
Article class: Scientific Article

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Abstract: Details are given of a method of performing a semi-automated complement fixation test for the diagnosis of bovine leptospirosis. A “Dynatiter” machine is used which enables 288 sera to be tested per hour. In a comparative study it was shown that using this semi-automated test fewer than 5% of antibody titres differed from those obtained using a manual test, either with single antigens or a polyvalent antigen.

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