Serum and tissue enzyme profiles of goats

Authors: Carthew GC, Kramer JW
Publication: New Zealand Veterinary Journal, Volume 33, Issue 6, pp 91-93, Jun 1985
Publisher: Taylor and Francis

Animal type: Goat, Livestock, Production animal, Ruminant
Subject Terms: Biochemistry/chemistry, Clinical pathology, Diagnostic procedures
Article class: Scientific Article

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Abstract: Serum enzyme activities of sorbitol debydrogenase, glutamate debydrogenase, gamma glutamyltransferase, alkaline pbospbatase, aspartic aminotransferase, and creatine kinase, were measured in five clinically normal mixed-breed goats. Tissue activities of these enzymes were also measured in two goats. These basal serum values were then used to determine the response to treatment with carbon tetrachloride (CCl₄). The basal value for serum and hepatic tissue sorbitol dehydrogenase were appreciably greater for goats than previously reported for sheep and cattle. The change in the above serum enzymes after CCl₄ treatment resembled that in sheep, but the amount of sorbitol dehydrogenase increase was less than that in sheep. This study established basal tissue and serum enzyme activity values and demonstrated the efficacy of the use of changes in serum S.D.H. and G.D.H. activity as indicators of acite hepatopathy in goats.

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