Multiple defects in an aborted bovine foetus associated with chromosomal trisomy

Authors: Rousseaux CG, Schmutz SM, Coates JW
Publication: New Zealand Veterinary Journal, Volume 35, Issue 10, pp 173-174, Oct 1987
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Clinical pathology, Diagnostic procedures, Congenital disease, Genetics, Pathology
Article class: Clinical Communication

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Abstract: An aborted full-term bovine foetus bad multisystemic anomalies that included a heart defect, cleft palate, pulmonary hypoplasia and kyphoscoliosis. Karyotyping using pericardial sac fibroblast cells indicated that the foetal cells were trisomic. Trypsin-banding procedures and Giemsa staining revealed that the extra chromosome was presumptively Chromosome 27. This is the first report of chromosomal trisomy 27 in an abnormal bovine foetus, and highlights the significance of chromosomal aberrations as a cause of multi-systemic foetal anomalies.

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