Multigeneric resistance to benzimidazole anthelmintics in sheep

Authors: McKenna PB
Publication: New Zealand Veterinary Journal, Volume 37, Issue 2, pp 62-64, Jun 1989
Publisher: Taylor and Francis

Animal type: Livestock, Production animal, Ruminant, Sheep
Subject Terms: Alimentary system/gastroenterology, Anthelmintics, Parasite control, Parasites - internal, Animal remedies/veterinary medicines, Nematode, Treatment/therapy
Article class: Scientific Article

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Abstract: Benzimidazole resistance involving several gastrointestinal nematode genera on a single sheep farm in New Zealand is reported for the first time. A controlled slaughter trial showed that at the recommended dose rate of 12.5 mg/kg, mebendazole had efficacies of 0, 60, 66, 90, 54 and 38% against Haemonchus contortus, Ostertagia spp., Nematodirus spp., intestinal Trichostrongylus spp., Strongyloides spp. and Oesophagostomum venulosum, respectively. The relevance of such multigeneric resistance to possible future options for controlling anthelmintic resistant sheep trichostrongylids is briefly discussed.

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