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Chronic renal failure in young Old English Sheepdogs

Authors: Cayzer J, Jones BR, Chen W, Jones JM
Publication: New Zealand Veterinary Journal, Volume 38, Issue 3, pp 118-121, Sep 1990
Publisher: Taylor and Francis

Animal type: Companion animal, Dog
Subject Terms: Clinical pathology, Diagnostic procedures, Pathology, Kidney/renal disease, Urinary system/urology
Article class: Clinical Communication

Abstract: Chronic renal failure was diagnosed in three young Old English Sheepdogs. Clinical signs were characterised by ill-thrift, polydipsia, polyuria, nervous signs and behavioural changes. Laboratory findings showed azotaemia, non-regenerative anaemia, hyperphosphataemia and isosthenuria. The kidneys were characterised histologically by interstitial fibrosis, and thickening and calcification of the tubular and glomerular basement membrane. A familial incidence could not be confirmed in these cases.

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