IgA multiple myeloma in a dog

Authors: Cayzer J, Jones BR
Publication: New Zealand Veterinary Journal, Volume 39, Issue 4, pp 139-144, Dec 1991
Publisher: Taylor and Francis

Animal type: Companion animal, Dog
Subject Terms: Clinical pathology, Diagnostic procedures, Neoplasia, Oncology, Skeletal/bone/cartilage
Article class: Clinical Communication

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Abstract: Multiple myeloma was diagnosed in a lo-year-old female Labrador which showed signs of weight loss, lethargy and skeletal pain. Radiography revealed well circumscribed osteolytic lesions in vertebrae, sternebrae, and the left humerus and radius along with generalised osteoporosis. The number of plasma cells in the bone marrow was increased and the serum gamma globulin concentration was elevated. Treatment with cyclophosphamide, mephalan and prednisone successfully controlled the malignancy but also resulted in suppression of the bone marrow. There was a remission time of 21.5 months.

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