Persistent anthelmintic activity of abamectin injection in cattle

Authors: Eagleson JS, Scott PG, Gross SJ
Publication: New Zealand Veterinary Journal, Volume 40, Issue 1, pp 21-23, Mar 1992
Publisher: Taylor and Francis

Animal type: Cattle, Livestock, Production animal, Ruminant
Subject Terms: Alimentary system/gastroenterology, Animal remedies/veterinary medicines, Anthelmintics, Parasite control, Parasites - internal, Treatment/therapy, Nematode, Pharmacology
Article class: Scientific Article

---

Abstract: The duration of the anthelmintic activity of abamectin administered by subctitaneous injection at 200 µg/kg was determined using induced infections of Hqnonchus placei, Ostertagia ostertagi, Cooperia spp., and Oesophagostomum radiatum in cattle. Twenty-four Friesian calves, raised under worm-free conditions, were assigned to four groups of six animals using a randomised block design based on bodyweight. One group acted as untreated controls and the other three were treated with abamectin 14, 10 or 7 days before infection. At slaughter, 50-52 days after treatment (36-38 days after infection), efficacy was greater than 98-99% against all the parasite species for the groups challenged 10 and 7 days after treatment, whereas no significant activity could be demonstrated 14 days after treatment.

---