Comment on anthelmintic use in goats and the effect of route of administration

Authors: McKenna PB
Publication: New Zealand Veterinary Journal, Volume 42, Issue 4, pp 156, Aug 1994
Publisher: Taylor and Francis

Animal type: Goat, Livestock, Production animal, Ruminant
Subject Terms: Alimentary system/gastroenterology, Animal remedies/veterinary medicines, Anthelmintics, Parasite control, Parasites - internal, Nematode, Treatment/therapy
Article class: Correspondence

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Abstract: In a recent publication in this journal, administration of oral and injectable moxidectin (Vetdectin, Cyanamid N.Z. Ltd) to goats was found to result in faecal egg count reductions of 0% and 84% respectively, in infections that were predominantly composed of Ostertagia spp. The author considered that these results raised issues pertaining to the relative effectiveness of different routes of anthelmintic administration in goats and further suggested, as the animals were suffering from “water belly” at the time of treatment, that the occurrence of this syndrome may also have affected the pharmacodynamics of the anthelmintic. While both route of administration and host physiological factors are recognised as important determinants of anthelmintic performance, I nonetheless find it surprising that no consideration appears to have been given to the possibility of anthelmintic resistance being involved in this case…

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