Efficacy of ivermectin against benzimidazole-resistant Nematodirus spathiger in sheep

Authors: Whelan NC, Lees S, Alexander AM, Charleston WAG
Publication: New Zealand Veterinary Journal, Volume 43, Issue 3, pp 99-100, Jun 1995
Publisher: Taylor and Francis

Animal type: Livestock, Production animal, Ruminant, Sheep
Subject Terms: Alimentary system/gastroenterology, Animal remedies/veterinary medicines, Anthelmintics, Parasite control, Parasites - internal, Treatment/therapy, Nematode
Article class: Scientific Article

---

Abstract: Eighteen helminth-free lambs were randomly allocated to six groups of three. Each lamb was dosed with 3300 infective larvae pooled from two isolates of Nematodirus spathiger known to be benzimidazole resistant. One lamb from each group was treated with oral ivermectin, one with oral oxfendazole and one left untreated 21 days after infection. All lambs were humanely killed 14 days later and small intestine worm counts performed. No Nematodirus were found in the ivermectin-treated lambs. Nematodirus numbers were reduced by 13% in oxfendazole-treated lambs relative to the control lambs.

---