The effect on creatinine kinase activity of freezing plasma from healthy foals

Authors: Lopez-Villalobos N, Rogers CW, Forsyth SF
Publication: New Zealand Veterinary Journal, Volume 54, Issue 5, pp 235-236, Oct 2006
Publisher: Taylor and Francis

Animal type: Horse, Livestock
Subject Terms: Biochemistry/chemistry, Circulatory system/haematology, Treatment/therapy, Clinical pathology, Diagnostic procedures
Article class: Short Communication

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Abstract: AIM: To assess the stability of creatine kinase (CK) activity in plasma collected from healthy foals and frozen at –20°C for up to 12 weeks.
METHODS: Samples of venous blood drawn from 25 foals were analysed for CK activity soon after collection, and again after 1 and 12 weeks of freezing at –20°C.
RESULTS: CK activity decreased (p<0.001) between Week 0 and Week 1 and between Week 0 and Week 12.
Conclusions and Clinical Relevance: Decreases in CK activity were statistically significant but clinically insignificant.
KEY WORDS: Creatine kinase, freezing, foal

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